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Vaccination Events in Massachusetts: 1721 to 2020

History of Important Vaccination Events  in Massachusetts: 1721 to 2020 The history of vaccination in America begins, and continues to be deeply connected, with the pubic health and medical innovations in Massachusetts. This chronology supplements the research done for my book, Germs at Bay: Politics Public health and American Quarantine .   This Chronology covers the introduction of smallpox inoculation in 1721, the discovery of cowpox vaccination in 1796, and the expansion of the vaccine concept to other diseases in the 20th century.  The detailed chronology takes the reader all the way to the Covid-19 vaccines of 2020. June 26, 1721 Boylston Conducts First American Inoculation Program : After much research by Cotton Mather, the first inoculation in American history was completed by Dr. Zabdiel Boylston at Boston.  1722 Boylston Completes the First Inoculation Program : A total of 5,989 persons are infected with smallpox and 844 die from their infections. Dr. Boylston with help f